Download [EPUB/PDF] Biomaterials For Cancer Therapeutics

Biomaterials for Cancer Therapeutics

Medical / By Kinam Park / 2020-03-05

Author: Kinam Park

Publisher: Woodhead Publishing

ISBN: 9780081029848

Category: Medical

Page: 782

View: 620

Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion. Provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, treatment and prevention of cancer Discusses how the properties of specific biomaterials make them important in cancer treatment Covers synthetic vaccines, proteins and polymers for cancer therapeutics

Biomaterials for Cancer Therapeutics

Technology & Engineering / By Kinam Park / 2013-11-23

Author: Kinam Park

Publisher: Elsevier

ISBN: 9780857096760

Category: Technology & Engineering

Page: 530

View: 775

Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction. This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials. A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer Discusses the fundamentals of biomaterials for cancer therapeutics Discusses synthetic vaccines, proteins and polymers for cancer therapeutics

Engineering PH-responsive Biomaterials for Cancer Immunotherapy

/ By Meilyn Sylvestre / 2021

Author: Meilyn Sylvestre

Publisher:

ISBN: OCLC:1302725437

Category:

Page: 252

View: 181

Recent advances in immunotherapy have transformed cancer treatment, while highlighting the complex interactions between the immune system and tumors. For delivery of unstable molecules or immunogenic agents, these therapies often employ nanoformulations to deliver therapeutics to diseased tissue while minimizing off-target toxicity. However, delivery of these carriers is severely limited by numerous biological barriers, preventing therapies from reaching sufficient therapeutic concentrations. Carrier accumulation can be enhanced by incorporation of passive and active targeting, and/or stimuli-responsive elements to help steer the carrier to the appropriate diseased tissues, cells, and intracellular compartments. In this work, we seek to engineer new therapies to enhance targeting and delivery of cancer therapeutics by combining both active and passive targeting strategies. Part I motivates tumor-associated macrophages as immunotherapy targets (Chapter 1), leading into our first approach in which we identified a novel targeting ligand that binds to human tumor-associated macrophages and monocytes (Chapter 2). Part II discusses the challenges of peptide delivery in oncology applications (Chapter 3), prefacing our designed peptide-polymer conjugates that passively accumulate in tumors and respond to external pH to facilitate intracellular peptide delivery upon cellular internalization. Using this strategy, we designed a polymeric delivery system to safely deliver (Chapter 4) a variety of immunogenic peptides (Chapters 5, 6, and 7). Part III outlines the challenges in delivering therapeutics past the blood-brain barrier (Chapter 8), and reports the progress on the development of targeted nanoparticles for brain cancer treatment (Chapter 9).

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Medical / By Prashant Kesharwani / 2019-07-08

Author: Prashant Kesharwani

Publisher: Academic Press

ISBN: 9780128173312

Category: Medical

Page: 432

View: 815

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

Advanced Porous Biomaterials for Drug Delivery Applications

Medical / By Mahaveer Kurkuri / 2022-11-30

Author: Mahaveer Kurkuri

Publisher: CRC Press

ISBN: 9781000783889

Category: Medical

Page: 469

View: 468

Advanced Porous Biomaterials for Drug Delivery Applications probes cutting-edge progress in the application of advanced porous biomaterials in drug delivery fields. These biomaterials offer promise in improving upon the design, cost, and creation of potent novel drug delivery systems. The book focuses on two categories: nature engineered and synthetic advanced porous biomaterials, with a wide range of low-cost porous biomaterial-based systems that have been used for the delivery of diverse drugs through in vitro/in vivo approaches. Details how advanced porous biomaterial-assisted systems improve essential properties in drug delivery applications Explains how advanced porous biomaterials systems are being used and explored to improve overall performances of drug delivery systems in mitigating a variety of diseases Emphasizes major applications in drug delivery such as controlled release, cancer therapy, and targeted delivery, and with focus on oral, topical, and transdermal applications Focuses on both naturally available and synthetic low-cost advanced porous biomaterials and their role in enhancing important parameters in drug delivery applications Accessible to readers with bio and non-bio backgrounds This book is an ideal reference for academics, researchers, and industry professionals in the interdisciplinary fields of biomedicine and biomedical engineering, pharmaceuticals, materials science, and chemistry.

Nanostructures for Cancer Therapy

Technology & Engineering / By Alexandru Mihai Grumezescu / 2017-04-11

Author: Alexandru Mihai Grumezescu

Publisher: Elsevier

ISBN: 9780323461504

Category: Technology & Engineering

Page: 920

View: 306

Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics. In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents. The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer. Provides an examination of nanoparticle delivery systems for cancer treatment, illustrating how the use of nanotechnology can help provide more effective chemotherapeutic treatments Examines, in detail, the different types of nanomaterials used in cancer therapy, also explaining the effect of each Provides a cogent overview of recent developments in the use of nanostructured materials in chemotherapeutics, allowing readers to quickly familiarize themselves with this area

Bio-Nanomedicine for Cancer Therapy

Medical / By Flavia Fontana / 2021-02-04

Author: Flavia Fontana

Publisher: Springer Nature

ISBN: 9783030581749

Category: Medical

Page: 360

View: 299

The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.

Marine Biomaterials

Medical / By Sougata Jana / 2022-02-14

Author: Sougata Jana

Publisher: Springer Nature

ISBN: 9789811647871

Category: Medical

Page: 453

View: 378

This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.

Nanoparticles in Cancer Therapy: Novel Concepts, Mechanisms and Applications

/ By Qingxin Mu / 2019-04-03

Author: Qingxin Mu

Publisher: Frontiers Media SA

ISBN: 9782889458103

Category:

Page: 162

View: 924

Since the invention of nanomedicine decades ago, considerable progresses have been made, especially with cancer as a target. Nanoparticles have been proven to be powerful imaging tools or potent agents for cancer diagnosis, treatment and prevention. Active research spread from fundamental research to clinical investigations. This topic intends to cover several important aspects in this field including nanocarrier development, gene delivery, intrinsically active nanoparticles, tumor microenvironment, immunology, and toxicity.

Nanooncology

Technology & Engineering / By Gil Gonçalves / 2018-06-01

Author: Gil Gonçalves

Publisher: Springer

ISBN: 9783319898780

Category: Technology & Engineering

Page: 455

View: 115

This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.

New Trends in Smart Nanostructured Biomaterials in Health Sciences

Medical / By Gil Goncalves / 2022-10-07

Author: Gil Goncalves

Publisher: Elsevier

ISBN: 9780323885669

Category: Medical

Page: 442

View: 160

New Trends in Smart Nanostructured Biomaterials in Health Sciences provides guidance on the design and synthesis of nanostructured smart biomaterials, as well as the resultant therapeutic effects and associated biomedical applications of these novel materials. The book provides readers with a deeper understanding of these novel biomaterials and aids them in making informed decisions when selecting appropriate materials for tissue engineering and cancer therapy applications. It will be of specific interest to materials scientists, biomedical engineers, oncological scientists, tissue engineers and those working in regenerative medicine. Nanostructured smart materials have the special ability to respond to changes in the cell microenvironment, allowing for robust, biocompatible and rapidly adaptable, therapeutic and restorative action against a range of ailments. These materials are thus ideal candidates for use in tissue engineering and cancer therapy due to the varying nature of the cell microenvironment between persons, tissues and cancers. This book covers the design, synthesis, unique properties and application of smart biomaterials in these two key topic areas of tissue engineering and cancer therapeutics. Presents an overview of how smart biomaterials respond to changes in physiological factors and exogeneous stimuli and their impact in modern medicine Provides readers with the basis for designing, processing and characterizing advanced smart biomaterials Guides the reader through the mechanisms of tissue repair and cancer therapeutics by exploring the most relevant features of smart nanostructured materials

Nanobiomaterials in Cancer Therapy

Technology & Engineering / By Alexandru Grumezescu / 2016-03-22

Author: Alexandru Grumezescu

Publisher: William Andrew

ISBN: 9780323428866

Category: Technology & Engineering

Page: 588

View: 399

Nanobiomaterials in Cancer Therapy presents the major applications of nanobiomaterials in oncology, offering an up-to-date overview of the latest research in this field. Utilizing nanobiomaterials, novel therapeutic approaches enable significant improvements in drug-loading capacity, formulation stability and drug efficiency. In this book, leading researchers from around the world share their expertise and unique insights. The book covers the fabrication methods of platforms for multimodal and combinatorial therapeutic options, along with simultaneous and real-time cancer imaging, and innovative approaches for oncology by passive or active pathways of multifunctional nanocarriers. The work also classifies and discusses engineered nanobiosystems for cancer therapy, prevention, and low cancer recurrence or relapse. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A comprehensive resource for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Discusses novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

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