Handbook of Toxicology of Chemical Warfare Agents, Third Edition covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures. Expanding on the second edition, Handbook of Toxicology of Chemical Warfare Agents has been completely updated, presenting the most recent advances in field. Brand new chapters include a new chapter on emergency preparedness, coverage of the chemical warfare agents used in Syria, the use of the Novichok agent in the UK, and more. Unites world-leading experts to bring you cutting-edge, agent-specific information on Chemical Warfare Agents (CWA) and their adverse effects on human and animal health, and the environment Provides you with all the information you need on CWA modes of action, detection, prevention, therapeutic treatment and countermeasures New to this edition: a full update to reflect the most recent advances in the field and new chapters on emergency preparedness, the chemical warfare agents used in Syria, and the use of the Novichok agent in the UK
This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book. This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with
The Illustrated Handbook of Toxicology is an impressive introduction to the complex field of toxicology. It also serves as a hands-on guide to various poison treatments and offers supplemental public health information.Each two-page unit features concise text on the left complemented by full-color illustrations on the opposing page. The expert author distinguishes harmful toxic substances and catalogues their specific effects on the human body, plants, animals, and the surrounding environment. The handbook also addresses cutting-edge topics, including biological warfare, modern toxicological methods, and threshold values.Features: Succinct, user-friendly organization allows readers to navigate the content with ease Over 500 detailed images and diagrams arranged on 150 full-color plates illustrate exposures and toxicological effects on humans, plants, and animals Well-researched, objective risk analysis on toxic exposures accompanies relevant images Extensive glossary of key toxicological terms provides readers with the accurate information they need to avoid dangerous confusion This is the ideal text for all medical students who want to supplement the toxicological information covered in their coursework, as well as for first responders to chemical accidents and poisonings.
The Handbook of Chemical and Biological Warfare Agents, Volume 1: Military Chemical and Toxic Industrial Agents, Third Edition provides rapid access to key data to response professionals and decision-makers on a broad range of agents and pathogens. This volume examines military chemical agents that were developed for their lethal effects and includes chapters on nerve agents, vesicants, urticants, convulsants, blood agents, and pulmonary agents. It also details toxic industrial materials that are considered potential threat for use as improvised agents. In addition to a discussion of each of these classes of agents, coverage includes detailed information on a broad spectrum of individual agents that have been used on the battlefield, stockpiled as weapons, used or threatened to be used by terrorists, or have been otherwise assessed by qualified law enforcement and response organizations and determined to be agents of significant concern The information presented in this edition has been updated and expanded; containing more information on toxicology, health effects, chemical and physical properties of individual agents, as well as protective actions needed at the scene of an incident. Key Features: Focuses on key information needed during an emergency response Provides updated toxicology, exposure hazards, physical-chemical data, and best practices with regard to the treatment of casualties Presents updated protective action distances, decontamination, and remediation information All data compiled is gathered from numerous sources and arranged into the current, easy-to-access format. In order to ensure accuracy, all data has been cross-checked over the widest variety of military, scientific and medical sources available. The Handbook of Chemical and Biological Warfare Agents, Volume 1: Military Chemical and Toxic Industrial Agents, Third Edition remains the gold-standard reference detailing the widest variety of military, scientific, and medical sources available
Extensively revised and updated, this second edition of the bestselling Handbook of Chemical and Biological Warfare Agents goes well beyond the “dirty thirty” commonly discussed agents and provides rapid access to a wide range of agents that can be used as weapons. This edition incorporates additional classes of agents, expands existing classes, and increases the number of agents described. Expanding the scope of the original, this edition is rich with scientific data and provides more information on the chemical, physical, and biological properties of these agents and their health effects. Highly organized and cross-referenced to provide instant access to the most authoritative data, this handbook is divided into classes based on the common military groupings of chemical, biological, and toxin agents. Additional classes are provided where the divisions are too broad for appropriate identification, along with classes for non-traditional agents and improvised industrial materials. At the end of each class section is detailed technical information about individual agents, components, precursors, and decomposition products within that class. Employing four indices along with the handbook’s own identification number, each entry follows a standard format for that class including toxicology, characteristics, hazards, protection, and medical response. Other information is provided where applicable such as chemical formula, routes of exposure, medicinal uses, threat or treaty listing, and descriptions of the disease as it appears in humans, animals, and plants. All values are based on a “standard” man model to allow for consistency of data and evaluations. Still the gold-standard reference in the field, Handbook of Chemical and Biological Warfare Agents, Second Edition raises the bar in terms of both quality and quantity and assures accuracy across the widest variety of military, scientific, and medical sources available.
Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more
The Handbook of Chemical and Biological Warfare Agents, Volume 2: Pathogens, Mid-Spectrum, and Incapacitating Agents, Third Edition provides rapid access to key data to response professionals and decision-makers on a broad range of agents and pathogens. This volume presents information on a wide range of chemical and biological agents. Chemical agents detailed in this volume are those that were developed specifically for their non-lethal potential. The biological agents described are militarily significant pathogens that could be weaponized to pose a threat to people, animals, or crops and other agricultural interests. Mid-spectrum agents, materials that do not fit clearly into either the Chemical or the Biological Weapons Conventions, include toxins and bioregulators. Entomological agents, the final class of agents discussed in volume, are arthropods that could pose a significant threat to a country’s agriculture infrastructure and be used to devastate its economy. They were proposed for inclusion in the Biological Weapons Convention but never adopted. In addition to a discussion of each of these classes of agents, coverage includes detailed information on a broad spectrum of individual agents that have been used on the battlefield, stockpiled as weapons, used or threatened to be used by terrorists, or have been otherwise assessed by qualified law enforcement and response organizations and determined to be agents of significant concern. The information presented in this edition has been updated and expanded to contain more information on toxicology, health effects, presentation of diseases, advances in medical care and treatment, as well as protective actions needed at the scene of an incident. Key Features: Focuses on the key information needed during an emergency response Provides updated toxicology, exposure hazards, physical-chemical data, and treatment of casualties Profiles the presentation of diseases in people, animals and plants Presents updated protective action distances, decontamination, and remediation information All data compiled is gathered from numerous sources and arranged into the current, easy-to-access format. In order to ensure accuracy, all data has been cross-checked over the widest variety of military, scientific and medical sources available. The Handbook of Chemical and Biological Warfare Agents, Volume 2: Pathogens, Mid-Spectrum, and Incapacitating Agents, Third Edition remains the gold-standard reference detailing the widest variety of military, scientific, and medical sources available.
Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection
Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects provides a general overview of the development and performance of different novel molecular frameworks as potent vehicles for sensing Chemical Weapons (CWs). The chapters are contributed by leading researchers in the areas of materials science, medical science, chemical science, and nanotechnology from industries, academics, government and private research institutions across the globe. It covers cover topics such as inorganic nanocomposites, hyperbranched polymers, and graphene heterojunctions for effective sensing of CW agents. This book is a highly valuable reference source for graduates, post-graduates, and research scholars primarily in the fields of materials science, medicinal chemistry, organic chemistry, and nanoscience and nanotechnology. In addition, almost all analytical techniques will be discussed, making this a first-rate reference for professors, students, and scientists in many industries. Provides an efficient, reliable, and highly versatile approach for the synthesis of different molecular systems suitable for diversity-oriented strategies, structure-activity studies and molecular tailoring for the sensing of chemical warfare agents Goes into depth on new binary organogels, discrete carbon nanomaterials (CNMs) and molecularly imprinted polymers (MIPs) and has endowed electrochemical chemosensors (ECCSs) with high selectivity and sensitivity towards the detection of chemical warfare agent Highlights in detail the detection of CWs by composite optical waveguide sensors, and describes disposable biofilm biosensors for sensitive detection of biotoxicity in water with treatment of nerve agent poisoning
For centuries, nations, armies and civilians have used toxic chemicals for nefarious purposes. Although forbidden from use during warfare, chemical weapons have an unfortunately long history of use as chemical agents of destruction. Accidental or intentional exposure of civilians to toxic chemicals frequently occurs. Chemical Warfare Agents & Treatments provides an overview of different classes of chemical warfare agents, starting from the extremely toxic organophosphorus nerve agents, followed by blister agents, blood agents, pulmonary agents, and incapacitating agents, and finally ending with the least toxic class, riot control agents. The e-book covers the physiological effects caused by these agents, the underlying mechanisms of action, and the available medical treatments (as of the writing of this work).