Human Flourishing in an Age of Gene Editing

Author: Erik Parens

Publisher: Oxford University Press

ISBN: 9780190940393

Category: Medical

Page: 240

View: 951

International uproar followed the recent announcement of the birth of twin girls whose genomes had been edited with a breakthrough DNA editing-technology. This technology, called clustered regularly interspaced short palindrome repeats or CRISPR-Cas9, can alter any DNA, including DNA in embryos, meaning that changes can be passed to the offspring of the person that embryo becomes. Should we use gene editing technologies to change ourselves, our children, and future generations to come? The potential uses of CRISPR-Cas9 and other gene editing technologies are unprecedented in human history. By using these technologies, we eradicate certain dreadful diseases. Altering human DNA, however, raises enormously difficult questions. Some of these questions are about safety: Can these technologies be deployed without posing an unreasonable risk of physical harm to current and future generations? Can all physical risks be adequately assessed, and responsibly managed? But gene editing technologies also raise other moral questions, which touch on deeply held, personal, cultural, and societal values: Might such technologies redefine what it means to be healthy, or normal, or cherished? Might they undermine relationships between parents and children, or exacerbate the gap between the haves and have-nots? The broadest form of this second kind of question is the focus of this book: What might gene editing--and related technologies--mean for human flourishing? In the new essays collected here, an interdisciplinary group of scholars asks age--old questions about the nature and well-being of humans in the context of a revolutionary new biotechnology--one that has the potential to change the genetic make-up of both existing people and future generations. Welcoming readers who study related issues and those not yet familiar with the formal study of bioethics, the authors of these essays open up a conversation about the ethics of gene editing. It is through this conversation that citizens can influence laws and the distribution of funding for science and medicine, that professional leaders can shape understanding and use of gene editing and related technologies by scientists, patients, and practitioners, and that individuals can make decisions about their own lives and the lives of their families.
Human Flourishing in an Age of Gene Editing

Author: Erik Parens

Publisher: Oxford University Press

ISBN: 9780190940386

Category: Medical

Page: 240

View: 686

International uproar followed the recent announcement of the birth of twin girls whose genomes had been edited with a breakthrough DNA editing-technology. This technology, called clustered regularly interspaced short palindrome repeats or CRISPR-Cas9, can alter any DNA, including DNA in embryos, meaning that changes can be passed to the offspring of the person that embryo becomes. Should we use gene editing technologies to change ourselves, our children, and future generations to come? The potential uses of CRISPR-Cas9 and other gene editing technologies are unprecedented in human history. By using these technologies, we eradicate certain dreadful diseases. Altering human DNA, however, raises enormously difficult questions. Some of these questions are about safety: Can these technologies be deployed without posing an unreasonable risk of physical harm to current and future generations? Can all physical risks be adequately assessed, and responsibly managed? But gene editing technologies also raise other moral questions, which touch on deeply held, personal, cultural, and societal values: Might such technologies redefine what it means to be healthy, or normal, or cherished? Might they undermine relationships between parents and children, or exacerbate the gap between the haves and have-nots? The broadest form of this second kind of question is the focus of this book: What might gene editing--and related technologies--mean for human flourishing? In the new essays collected here, an interdisciplinary group of scholars asks age--old questions about the nature and well-being of humans in the context of a revolutionary new biotechnology--one that has the potential to change the genetic make-up of both existing people and future generations. Welcoming readers who study related issues and those not yet familiar with the formal study of bioethics, the authors of these essays open up a conversation about the ethics of gene editing. It is through this conversation that citizens can influence laws and the distribution of funding for science and medicine, that professional leaders can shape understanding and use of gene editing and related technologies by scientists, patients, and practitioners, and that individuals can make decisions about their own lives and the lives of their families.
The Human Gene Editing Debate

Author: John H. Evans

Publisher: Oxford University Press

ISBN: 9780197519578

Category: Science

Page: 288

View: 336

In 2018 the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the pre-existing moral consensus, which had held for over fifty years before: while gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. If this line is passed over, scientists will be left without an agreed-upon ethical limit. What do we do now? John H. Evans here provides a meta-level guide to how these debates move forward and their significance to society. He explains how the bioethical debate has long been characterized as a slippery slope, with consensually ethical use at the top, nightmarish dystopia at the bottom, and specific agreed-upon limits in between, which draw the lines between the ethical and the unethical. Evans frames his analysis around these limits, or barriers. Historically they have existed to guide scientists and to prevent the debate from slipping down the metaphorical slope into unacceptable eugenicist possibilities, such as in Aldous Huxley's novel Brave New World or the movie Gattaca. Evans examines the history of how barriers were placed, then fell, then replaced by new ones, and discusses how these insights inform where the debate may head. He evaluates other proposed barriers relevant to where we are now, projects that most of the barriers suggested by scientists and bioethicists will not hold, and cautiously identifies a few that could serve as the moral boundary for the next generation. At a critical time in this new era of intervention in the human genome, The Human Gene Editing Debate provides a necessary, comprehensive analysis of the conversation's direction, past, present, and future.
Human Flourishing

Author: Andrew Briggs

Publisher: Oxford University Press

ISBN: 9780192590855

Category: Science

Page: 304

View: 369

'A careful and thoughtful provocation' (Justin Welby, Archbishop of Canterbury) Ambitiously placed at the intersection of scientific insights and spiritual wisdom, Human Flourishing prompts us to reflect on what constitutes a good life and the choices that can help achieve it. For thousands of years, humans have asked 'Why we are here?' and 'What makes for a good life?' At different times, different answers have held sway. Nowadays, there are more answers proposed than ever. Much of humanity still finds the ultimate answers to such questions in religion. But in countries across the globe, secular views are widely held. In any event, whether religious or secular, individuals, communities and governments still have to make decisions about what people get from life. This book therefore examines what is meant by human flourishing and see what it has to offer for those seeking after truth, meaning and purpose. This is a book written for anyone who wants a future for themselves, their children, and their fellow humans - a future that enables flourishing, pays due consideration to issues of truth and helps us find meaning and purpose in our lives. At a time when most of us are bombarded with messages about what we should or should not do to live healthily, attain a work-life balance and find meaning, a careful consideration of the contributions of both scientific insight and spiritual wisdom provides a new angle. This is therefore a book that not only helps readers clarify their views and see things afresh but also help them improve their own well-being in an age of AI and other new technologies.
Rechtliche Aspekte der Genom-Editierung an der menschlichen Keimbahn

Author: Jochen Taupitz

Publisher: Springer-Verlag

ISBN: 9783662590287

Category: Law

Page: 569

View: 964

Das Buch enthält 19 Landesberichte und eine rechtsvergleichende Analyse der rechtlichen Regelungen zum Verfahren der Genom-Editierung an der menschlichen Keimbahn. Es wird herausgearbeitet, welche gemeinsamen Werte die verschiedenen Rechtsordnungen verbinden und welche Unterschiede bestehen. Auf dieser Grundlage wird untersucht, ob eine internationale Regulierung der Thematik möglich ist und wie diese ausgestaltet sein könnte. Zudem soll untersucht werden, in wie weit die Regelungen anderer Länder als Modell für die deutsche Gesetzgebung dienen können.
Ethical Issues in Modern Medicine

Author: Bonnie Steinbock

Publisher: McGraw-Hill Humanities, Social Sciences & World Languages

ISBN: UOM:39015059188402

Category: Bioethics

Page: 868

View: 618

This comprehensive anthology represents the key issues and problems in the field of medical ethics through the most up-to-date readings and case studies available. Each of the book's six parts is prefaced with helpful introductions that raise important questions and skillfully contextualize the positions and main points of the articles that follow.
Designer Children

Author: Karen Peterson-Iyer

Publisher:

ISBN: UOM:39015060381335

Category: Religion

Page: 232

View: 507

Amazingly, for the first time in human history, couples interested in becoming parents may soon be able to directly pre-select or alter specific genetic characteristics of their offspring. However, this new capacity and its potential to be used for "good" or "evil" are of increasing and pressing moral concern. In Designer Children, Peterson-Iyer hopes to construct some moral ground under society's feet regarding genetic technology. She draws upon the best insights from Christian faith and from feminist thought in order to evaluate the various ways in which to genetically "shape" children. With great clarity and care, she employs the concept of "human flourishing"--as a vision and guide as we wade through the quagmire of ethical questions--to advance specific recommendations about three contemporary types of genetic manipulation: gene therapy to prevent cystic fibrosis; genetic enhancement of memory; and sex pre-selection.
Bioethics

Author: Warren T. Reich

Publisher: Macmillan Library Reference

ISBN: UOM:49015003476919

Category: Social Science

Page: 1152

View: 412

Extracted from the 5-volume "Encyclopedia of Bioethics", this book takes a look at the concentrated look at the legal, social, moral and health-related issues surrounding sex and reproduction.