Targets in Heterocyclic Systems

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Targets in Heterocyclic Systems

Author: Orazio A. Attanasi

Publisher: Royal Society of Chemistry

ISBN: 8886208243

Category: Science

Page: 308

View: 473

It is well known that heterocyclic derivatives represent almost half of the several million chemical species discovered to date. The importance of these compounds in many branches of chemistry ensures further investigation and attention. This series aims to stimulate creativity and innovation by including research by leading authorities. As well as highlights of interesting developments in specific areas, there are also comprehensive reviews reporting the overall state-of-the-art. Targets in Heterocyclic Systems Volume 2 will be welcomed by researchers in areas as diverse as polymeric, medicinal and agricultural chemistry, as well as in the dyestuffs and biochemical industries.

Targets in Heterocyclic Systems

Science / By /
Targets in Heterocyclic Systems

Author: Orazio A. Attanasi

Publisher: Royal Society of Chemistry

ISBN: UVA:X004586837

Category: Science

Page: 466

View: 642

It is well-known that heterocyclic derivatives represent almost half of the several million chemical species discovered to date. The importance of these compounds in many branches of chemistry ensures further investigation and attention. This series aims to stimulate creativity and innovation by including research by leading authorities. In addition to highlights of interesting developments in specific areas, there are also comprehensive reviews reporting the overall state-of-the-art. "Targets in Heterocyclic Systems Volume 4" will be welcomed by researchers and industrialists with an interest in the synthesis and reactivity of heterorings.

The Diels-Alder Reaction

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The Diels-Alder Reaction

Author: Francesco Fringuelli

Publisher: John Wiley & Sons

ISBN: 047180343X

Category: Science

Page: 364

View: 299

This is the first book to collect together 70 years worth of experimental procedures that have been developed to perfom the Diels-Alder reaction. It begins with the fundamental principles and contains numerous graphical abstracts to present the basic concepts in a concise and pictorial way. Covering the theory and synthetic applications of the experimental methods it describes the procedures and techniques and includes reports on industrial applications. * Illustrates the fundamental principles and summarises experimental methods used to carry out the Diels-Alder reaction * Contains physical and catalytic methods to enhance the selectivity of the Diels-Alder reaction * Includes procedures for cycloaddition accomplished in conventional and unconventional media * Outlines the practical procedures * Focuses on clean syntheses and green chemistry * Provides a single source for relevant information and includes over 1,000 references The Diels-Alder reaction mechanism was first published in 1928 and in the last 70 years has become the most commonly used and studied mechanism in organic chemistry.

Modern Heterocyclic Chemistry, 4 Volumes

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Modern Heterocyclic Chemistry, 4 Volumes

Author: Julio Alvarez-Builla

Publisher: John Wiley & Sons

ISBN: 9783527332014

Category: Science

Page: 2531

View: 510

Since vitamins, hormones, antibiotics, pharmaceuticals, dyes and many other products all contain heterocycles, they play an important role in our everyday life. The must-have reference in the field of heterocyclic compounds, comprehensively covering their synthesis, structure and chemical and physical properties in four volumes. It presents a wealth of information but stays userfriendly by focussing on the important facts. An up-to-date source of high-quality information for all organic and medicinal chemists working in this field in industry and academia.

Nitroazoles: Synthesis, Structure and Applications

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Nitroazoles: Synthesis, Structure and Applications

Author: Lyudmila Larina

Publisher: Springer Science & Business Media

ISBN: 0387980709

Category: Science

Page: 441

View: 430

This volume is devoted to the synthesis, application, structure, and physicochemical properties of nitroazoles (five-membered aromatic compounds). The book is unique in providing the first comprehensive treatment of nitroazoles.

Heterocyclic Mesomeric Betaines and Mesoionic Compounds

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Heterocyclic Mesomeric Betaines and Mesoionic Compounds

Author:

Publisher: Academic Press

ISBN: 9780323988629

Category: Science

Page: 452

View: 953

Heterocyclic Mesomeric Betaines and Mesoionic Compounds, Volume 137 in the Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Heterocyclic Mesomeric Betaines, Type A Mesoionic Compounds (1980-2020), Type B Mesoionic Compounds (1980-2020), Recent Developments in the Chemistry of Heteroporphyrins, Carbaporphyrins and Related Systems, Heterocyclic Zwitterions Based on Coupled Polymethines, Meso-ionic Compounds reproduced from Adv. Heterocycl. Chem. 1976, 19, 1-122., and Meso-ionic Heterocycles (1976-1980) reproduced from Tetrahedron, 1982, 38, 2965-3011. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Advances in Heterocyclic Chemistry series Updated release includes the latest information on Betaine

Advances in Heterocyclic Chemistry

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Advances in Heterocyclic Chemistry

Author:

Publisher: Academic Press

ISBN: 9780128209868

Category: Science

Page: 304

View: 191

Advances in Heterocyclic Chemistry, Volume 133 is the latest release in this definitive series of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review contains comprehensive chapters on Organosilicon azoles: Structure, silylotropy and NMR spectroscopy, Recent advances in the Nenitzescu indole synthesis (1990–2019), One-pot reactions of three-membered rings giving N,O,S-heterocycles, Organometallic complexes of functionalized chelating azines: Part 2, and more. Presents the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews as written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Incorporation of Heterocycles into Combinatorial Chemistry

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Incorporation of Heterocycles into Combinatorial Chemistry

Author: Eugene Babaev

Publisher: Springer

ISBN: 3319500139

Category: Science

Page: 117

View: 247

The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with the solid phase synthesis which is shown on various techniques – BillBoard, tea-bag, and Lantern devices, and demonstrated on heterocyclic examples and protocols. In the third chapter the tools for accelerating chemical synthesis – solid phase and liquid phase – are reviewed. Here the techniques of parallel refluxing (including microwave and flow technique) and parallel separation (filtration, centrifugation, evaporation, and chromatography) are described. In the chapters 4 and 5 the author goes on to describe how the liquid phase synthesis of heterocycles (reductive amination and Ugi reaction of heterocycles) is illustrated with the use of semi-automated protocols. Finally, the design of combinatorial libraries of heterocycles is reviewed including the original author’s findings.

Fluorine in Heterocyclic Chemistry Volume 1

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Fluorine in Heterocyclic Chemistry Volume 1

Author: Valentine Nenajdenko

Publisher: Springer

ISBN: 9783319043463

Category: Science

Page: 681

View: 168

This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.

Advances in Heterocyclic Chemistry

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Advances in Heterocyclic Chemistry

Author: Eric Scriven

Publisher: Academic Press

ISBN: 9780323901284

Category: Science

Page: 330

View: 506

Advances in Heterocyclic Chemistry, Volume 136 is the latest release in this definitive series in the field of heterocyclic chemistry, one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds

Green Synthetic Approaches for Biologically Relevant Heterocycles

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Green Synthetic Approaches for Biologically Relevant Heterocycles

Author: Goutam Brahmachari

Publisher: Elsevier

ISBN: 9780128005903

Category: Science

Page: 632

View: 703

Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry. Includes global coverage of a wide variety of green synthetic techniques Features cutting-edge research in the field of bioactive heterocyclic compounds Focuses extensively on applications, with numerous examples of biologically relevant heterocycles