Author: Departments of Neurology R. John Leigh Professor, Neuroscience Otolaryngology and Biomedical Engineering Case Western Reserve University University Hospitals and Veterans Affairs Medical Center Cleveland Ohio
Publisher: Oxford University Press, USA
The Neurology of Eye Movements provides clinicians with a synthesis of current scientific information that can be applied to the diagnosis and treatment of disorders of ocular motility. Basic scientists will also benefit from descriptions of how data from anatomical, electrophysiological, pharmacological, and imaging studies can be directly applied to the study of disease. By critically reviewing such basic studies, the authors build a conceptual framework that can be applied to the interpretation of abnormal ocular motor behavior at the bedside. These syntheses are summarized in displays, new figures, schematics and tables. Early chapters discuss the visual need and neural basis for each functional class of eye movements. Two large chapters deal with the evaluation of double vision and systematically evaluate how many disorders of the central nervous system affect eye movements. This edition has been extensively rewritten, and contains many new figures and an up-to-date section on the treatment of abnormal eye movements such as nystagmus. A major innovation has been the development of an option to read the book from a compact disc, make use of hypertext links (which bridge basic science to clinical issues), and view the major disorders of eye movements in over 60 video clips. This volume will provide pertinent, up-to-date information to neurologists, neuroscientists, ophthalmologists, visual scientists, otalaryngologists, optometrists, biomedical engineers, and psychologists.
The Neurology of Eye Movements, edition 5 has two interrelated parts. The first comprises a modern synthesis of the anatomical, physiological, and pharmacological substrate for eye movements, including current views on the reflexive and voluntary control of gaze. This synthesis is based on electrophysiological and inactivation studies in macaque, and behavioural studies in humans that incorporate functional imaging and transcranial magnetic stimulation (TMS) in normals, and clinicopathological studies in patients with neurological, visual, or vestibular disorders.
This new edition of Leigh and Zee's The Neurology of Eye Movements is available as an enhanced edition for the first time. Your purchase of the print version includes access to the online version via Oxford Medicine Online. By activating your unique access code, you can discover more than 200videos, view and enlarge nearly 250 high resolution images, and annotate the work for future personal reference. The 5th edition of The Neurology of Eye Movements has two interrelated parts. The first comprises a modern synthesis of the anatomical, physiological, and pharmacological substrate for eye movements, including current views on the reflexive and voluntary control of gaze. This synthesis is based onelectrophysiological and inactivation studies in macaque, and behavioural studies in humans that incorporate functional imaging and transcranial magnetic stimulation (TMS) in normals, and clinicopathological studies in patients with neurological, visual, or vestibular disorders. Sophisticatedexperimental paradigms have been applied to both species to explore aspects of cognition, memory, volition, and reward. This large body of research has demonstrated the power of eye movements as experimental tools. The second part of the book applies this synthesis to the clinical and laboratoryevaluation of patients with abnormal eye movements due to a broad range of disorders - from muscular dystrophy, and genetic disorders, to dementia, including visual and vestibular conditions. By placing links to figures, tables, boxes, and videos, a synthesis of basic research and clinical findings is provided, that may shed new light on disease processes and provide insights on normal brain function.
There is perhaps no area of neuro-ophthalmology that is advancing more rapidly with respect to an understanding of its anatomy and physiology than the ocular motor system. For this reason, it is difficult not only to keep up with the latest information concerning the basic mechanisms involved in the control of eye movements but also to remain up to date regarding the pathophysiology of specific disorders of eye movement. The material in this book is derived from a two-day course on eye movements held in The Netherlands in 1986. The course was designed as an introduction to the normal ocular motor system and to disorders of eye movements and was aimed toward orthoptists, ophthalmolo gists, optometrists, neurologists, and neurosurgeons. The chapters in this book were compiled by a trio of experts in the field of eye movements and contain discussions of anatomy and physiology of the ocular motor system, techniques of examination of patients with diplopia, and pathophysiology of specific disorders of ocular motility. Many of the authors of these chapters are among the most active investigators of eye movements in the world today, and their comments thus reflect the latest information in the field. This text is both basic and com prehensive and thus has something for everyone, from the student just beginning a study of the ocular motor system to the seasoned 'veteran' who wishes to know the latest information regarding central ocular motor control mechanisms. Neil R.
Eye Movement Disorders, by Dr. Agnes Wong, fills a great void in the Ophthalmology and Neurology literature by presenting eye movement disorders in a full-color, highly illustrative format. This text explains eye movement disorders in a concise yet comprehensive manner, which makes it an excellent reference book and an outstanding learning text for anyone trying to master the intricate relationship between eye movement disorders, and their underlying neuroanatomy and pathophysiology. Its easy-to-read and user-friendly approach will appeal to specialists in Ophthalmology, Neurology, and Neurosurgery who need a rapid reference on less familiar clinical problems. Key features include: Provides a coherent, concise, and easy to assimilate description and explanation of different eye movement disorders Presents over 100 full-color clinical photographs, radiographs, and color illustrations highlighting pertinent anatomy and brain pathways Highlights key information and important features through boxes, tables, and algorithms
A comprehensive book that reviews advances in ocular motor research on topics of general interest, rare, specialized or unique conditions, and pertinent basic neuroscience. A rare collection with contributions from basic neuroscientists, neurologists, and ophthalmologists. Includes dedicated chapters on mathematical models, pharmacotherapy, neuromodulation, motion perception, visual influence on eye movement, physiology of strabismus, and microsaccades. This book is dedicated to David Robinson - one of the pioneers of contemporary ocular motor and vestibular neuroscience.
This book describes the abnormal eye movements encountered in the critical care unit in everyday practice and elaborates on the mechanism and clinical significance behind them. Beginning with a thorough grounding of the basic anatomy and physiology ocular motor system and how they move the eyeballs; chapters explore the pathological descriptions of all the signs that a practicing neurologist, ophthalmologist, or emergency medicine specialist might see in other ICU's, as well as the diagnostic and prognostic evidence to answer the consult questions. Further chapters describe the abnormal ocular movements seen in the Neuro-ICU, Eye Movements in the Critical Care Setting is a comprehensive resource on eye movement in the critical care setting, and a useful guide for the neurologist, ophthalmologist, and emergency medical specialist and residents alike.
Eye-movement recording has become the method of choice in a wide variety of disciplines investigating how the mind and brain work. This volume brings together recent, high-quality eye-movement research from many different disciplines and, in doing so, presents a comprehensive overview of the state-of-the-art in eye-movement research. Sections include the history of eye-movement research, physiological and clinical studies of eye movements, transsaccadic integration, computational modelling of eye movements, reading, spoken language processing, attention and scene perception, and eye-movements in natural environments. Includes recent research from a variety of disciplines Divided into sections based on topic areas, with an overview chapter beginning each section Through the study of eye movements we can learn about the human mind, and eye movement recording has become the method of choice in many disciplines
In Eye Movement Disorders in Clinical Practice, a leading expert with over thirty years of teaching experience in neurology and neuro-ophthalmology offers comprehensive instruction on the diagnosis and treatment of all varieties of eye movement disorders. This important new text reflects the importance of correlating clinical signs of disorders in the oculomotor system with their neuroanatomic and neurophysiologic architecture. With its focus on signs and symptoms, the book advances lesion localization of eye movement disorders as the central clinical concern. The reader is also presented with a fresh review of bedside examination techniques in the ER, ICU, and walk-in clinic; productive ways of taking a clinical history; sign interpretation; source lesion localization; and, where appropriate, therapy. Unlike most of the titles on eye movement disorders, this book's chapters are arranged according to objective signs - like ptosis, neuromuscular syndromes, dizziness, vertigo, and syndromes of the medulla - rather than disease entities. This emphasis on the topographic analysis of symptoms and signs is contrary to the prevailing clinical approach in which responsibility for therapy typically drives the clinician to arrive at an etiological diagnosis as rapidly as possible. At risk in this process is nothing less than the art of clinical medicine. One of the aims of this book is to reverse this process, and move clinicians back to the observation and interpretation of signs. The text features over 100 clinical cases, each one challenging the reader to determine the neuroanatomical location of the patient's lesion. This exercise provides the anatomical guidance needed to make critical diagnostic and management decisions in patients who often present with abnormal eye movements. Dynamic and intellectually stimulating, Eye Movement Disorders in Clinical Practice is essential for any reader wanting to better understand eye movement disorders.
The Encyclopedia of the Neurological Sciences, Second Edition develops from the first edition, covering all areas of neurological sciences through over 1000 entries focused on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. The contributing authors represent all aspects of neurology from many viewpoints and disciplines to provide a complete overview of the field. Entries are designed to be understandable without detailed background knowledge in the subject matter, and cross-referencing and suggested further reading lead the reader from a basic knowledge of the subject to more advanced understanding. The easy-to-use 'encyclopedic-dictionary' format of the Encyclopedia of the Neurological Sciences, Second Edition features alphabetic entries, extensive cross-referencing, and a thorough index for quick reference. The wealth of information provided by these four volumes makes this reference work a trusted source of valuable information for a wide range of researchers, from undergraduate students to academic researchers. Provides comprehensive coverage of the field of neurological science in over 1,000 entries in 4 volumes "Encyclopedic-dictionary" format provides for concise, readable entries and easy searching Presents complete, up-to-date information on 32 separate areas of neurology Entries are supplemented with extensive cross-referencing, useful references to primary research articles, and an extensive index